Loss on Drying (LOD) Calculation Formula: Loss on Drying (LOD) is a common test used in pharmaceutical quality control to determine the amount of volatile matter lost from a sample during drying. It is widely used for APIs, excipients, intermediates, and pharmaceutical products to monitor moisture and other volatile substances present in the material. Although … Read more
Types of Dissolution: Dissolution testing is one of the most important quality control and formulation development tests in the pharmaceutical industry. It is used to understand how quickly and how completely an active pharmaceutical ingredient (API) is released from a dosage form into a dissolution medium. For tablets and capsules, dissolution is not simply a … Read more
How to Calculate Anhydrous and As-Is Assay by HPLC First of all understand that anhydrous assay and as-is assay are two different ways of expressing the same potency depending on whether water/moisture is excluded. 1. Basic concept If an API contains water, the as-is sample weight includes the water, while the anhydrous basis excludes the … Read more
Introduction: Know about API and Excipients Every pharmaceutical dosage form is made with a purpose. The active pharmaceutical ingredient, commonly called API, provides the therapeutic effect, while excipients help convert that API into a stable, manufacturable, effective, and patient-friendly medicine. Although patients usually focus on the drug name printed on a medicine pack, pharmaceutical scientists … Read more
Dissolution Method Development: Dissolution method development is an important part of pharmaceutical development because it helps us understand how quickly and how completely a drug substance is released from a dosage form. A good dissolution method should not simply produce a passing result; it should provide meaningful information about the performance of the formulation and … Read more