Generic vs Branded Medicines: Introduction: generic medicines contain the same active ingredient, dosage, strength, and therapeutic effect but are usually sold at a lower cost after the original patent expires. Health authorities such as the World Health Organization and U.S. Food and Drug Administration state that approved generic medicines must meet the same quality, safety, … Read more
Difference between pH and pKa What Is pH The term “pH” indicates how basic or acidic a given solution is; therefore, it indicates the amount of H+ ions found within the respective solution(s). The following examples show how to classify various pH values and the amount of acidity in each scenario: pH Value = Acidic … Read more
Columns in HPLC 8 Types of HPLC Columns Explained: C8, C18, and More (Complete Guide) High Performance Liquid Chromatography (HPLC) is one of the most powerful analytical techniques used in pharmaceuticals, chemicals, food testing, and research laboratories. While pumps, detectors, and mobile phases are important, the HPLC column is the heart of the entire system. … Read more
Polar and nonpolar solvent Introduction: What Is a Solvent A solvent is a substance that dissolves another substance (called the solute) to form a solution. The solvent is usually present in a larger amount than the solute. For example: Water dissolving salt, Alcohol dissolving perfumes, Hexane dissolving oils The ability of a solvent to dissolve … Read more
Diluent selection during method development of HPLC Diluent selection during method development of HPLC Why Diluent Selection Matters in HPLC High-Performance Liquid Chromatography (HPLC) is one of the most powerful analytical techniques used in pharmaceutical, chemical, food, and environmental laboratories. While much attention is given to column selection, mobile phase composition, and detector settings, diluent … Read more
